The dynamic internal fluidity of nuclear MORC2 condensates, rather than their mere assembly, is strictly required for transcriptional regulation and is selectively disrupted by neuropathy-linked ...
Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered ...
Researchers led by Prof. XU Zhiheng from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, revealed the important roles of POSH phase separation and its ...