Head and neck cancers display notable heterogeneity in their immune cell infiltrates, which reflect intricate spatial arrangements and dynamic networks of ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Frontiers in Immunology has opened submissions for studies on spatial immune diversity in head and neck cancer, aiming to advance precision immunotherapy. The effort encourages use of cutting-edge ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Researchers demonstrate improved spatial mapping technology that enhances transcript detection, identifies key tumor cell ...

The advent of single-cell omics technologies has revolutionized our understanding of the complex cellular landscape in cancer. Traditional bulk sequencing ...

Macrophages, key regulators of tissue health and immune defense, are among the most abundant immune cells in solid tumors. Their role in cancer has been difficult to define because even closely ...