In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.
Key market opportunities lie in developing IL-6 inhibitors for underexplored indications like atherosclerotic cardiovascular disease and thyroid eye disease. The IL-6 targeted therapy market gains ...
INDIGO Biosciences today announced the launch of its Transrepression Assay Services, expanding the company’s cell-based reporter assay capabilities for drug discovery teams studying pathway cross-talk ...
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...
Researchers say findings may have relevance to understanding cell biological pathways that contribute to nerve repair after injury or neurodegeneration.
Objective B-cell activating factor (BAFF) is essential for B-cell survival and innate immune activation, and its ...
Research into the LL-37 peptide reveals it acts as a complex biological messenger, far beyond its known role in basic immune ...
Non-immune cells play a crucial and often underappreciated role in host defense against invading pathogens. Beyond serving as passive physical barriers, ...
Immune cell therapies have transformed the treatment of certain blood cancers over the past decade. However, when it comes to ...
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