Randomized controlled trials could be harming nonprofits, experts argue

In the 1940s, medical researchers began using randomized controlled trials to assess the efficacy of health interventions. In ...
Medicine Buffalo

Randomization Techniques and Clinical Trial Data Management I

Randomization Techniques (60 minutes): In this workshop, the rationale behind randomized experiments will be explained. Descriptions of commonly utilized randomization algorithms will be presented, ...
The New England Journal of Medicine

Azithromycin to Reduce Mortality — An Adaptive Cluster-Randomized Trial

Twice-yearly mass distribution of azithromycin to children is a promising intervention to reduce childhood mortality in sub-Saharan Africa. The World Health Organization recommended restricting ...
RAPS

Breakthrough Designation: Pivotal Trials Lack Randomization, Double-Blinding and Control Groups

Breakthrough Designation: Pivotal Trials Lack Randomization, Double-Blinding and Control Groups A review of all therapeutics receiving a breakthrough designation and approved from 2012 to 2017 found a ...
Seeking Alpha

MoonLake completes patient randomization ahead of schedule for its Phase 2 trial in active psoriatic arthritis (PsA) and provides calendar of next readouts

Randomization target of 200 patients completed ahead of schedule in the ARGO PsA trial Top-line 12-week results of the ARGO trial in PsA for the novel IL-17A and IL-17F inhibiting Nanobody ® ...
TCTMD

Two Neutral IVUS Trials in Complex PCI—and One Positive—Spark Debate

NEW ORLEANS, LA—Three trials comparing IVUS with angiography for PCI guidance in patients with complex coronary artery disease took many attendees of American College of Cardiology (ACC) 2026 ...
The New England Journal of Medicine

Randomized Trial of Adjunctive Prednisolone for Kawasaki Disease

In this multicenter, open-label, randomized, controlled trial in China, we assigned participants with newly diagnosed Kawasaki disease in a 1:1 ratio to receive prednisolone plus standard treatment or ...
Business Insider

Transgene Completes Patient Randomization in Phase 2 Part of Clinical Trial Evaluating TG4050 in the Adjuvant Treatment of Head and Neck Cancer

Two-year disease-free survival from evaluable Phase 2 patients expected by the end of Q1 2028. Strasbourg, France, April 13, 2026, 8:00 a.m. CET – Transgene (Euronext Paris: TNG), a biotech company ...
Business Insider

HMNC Brain Health Completes Patient Randomization for Phase 2b OLIVE Trial for Major Depressive Disorder

MUNICH, Jan. 10, 2025 (GLOBE NEWSWIRE) -- HMNC Brain Health (“HMNC”), a clinical-stage precision psychiatry biopharma company pioneering personalized treatments powered by predictive companion ...
STAT

I tried to design a clinical trial for a supplement. 5 things got in the way

Felicione is an independent clinical research scientist and principal investigator. Walk into any drugstore, natural market, or Costco and you’ll find a dazzling array of supplements promising ...