FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...
Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...
Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...
This Scientific Reports Collection welcomes original research on Metabolic reprogramming in immune-mediated disorders. Narrative review articles are also welcomed, to our sister journal Scientific ...
Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...
An intestinal pathogen reshapes the gut environment to fuel its own colonization and cause diseases, a multi-institutional ...
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Cracking the code of adenocarcinoma at its roots
Early warning signs: Inflammation and genetic mutations can reprogram healthy glandular cells into precancerous states, setting the stage for adenocarcinoma formation. Molecular breakthroughs: ...
Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called pro-aging metabolic reprogramming (PAMRP), which could change our ...
Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called Pro-Aging Metabolic Reprogramming (PAMRP), which could change our ...
hLife adopts format-free submission. Format-free submission means that, provided you include everything necessary for review ...
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