It is the computational processing of images that reveals the finest details of a sample placed under all kinds of different light microscopes. Even though this processing has come a long way, there ...

The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

A new dual-light microscope lets researchers observe micro- and nanoscale activity inside living cells without using dyes. The system captures both detailed structures and tiny moving particles at ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...

Advanced light microscopy techniques are giving scientists a new understanding of human biology and what goes wrong in diseases Katarina Zimmer, Knowable Magazine Key takeaways: Super-resolution ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

QIScope: When imaging low protein levels in live cells on the high-sensitivity QIScope, bioluminescence (blue) significantly outperforms fluorescence (green). (Courtesy: Ruyu Ma - Helmholtz Munich) A ...

SLICE addresses one of the most significant challenges in modern biological research: the limited accessibility of high-performance light sheet microscopy due to high costs and complex infrastructure ...