New targeting discovery: Researchers found that DNA sequences can guide methylation machinery, a shift from the belief that ...

A decline in the expression of the epigenetic regulator Setd8 in neural stem cells (NSCs) during early adulthood leads to chromatin condensation and reduced gene expression, suppressing NSC ...

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary ...

This Research Topic is one volume within the series "The Future of Checkpoint Immunotherapy: New Roads Ahead". Please see the ...

The roles of GPER in (A) tumor epigenetic reprogramming, (B) EMT, (C) breast CSCs, and (D) EMR are shown. GPER, G protein-coupled estrogen receptor; EMT, epithelial to mesenchymal transition; CSCs, ...

The global aquaculture industry faces an urgent need to eliminate antibiotic dependency while sustaining productivity against increasingly complex disease ...

As people age, most maintain normal blood sugar even as insulin resistance tends to rise. New research suggests that ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...